Global consumption, production, and trade of livestock products have increased rapidly in the last two decades and are expected to continue. At the same time, safety concerns regarding human and animal disease associated with livestock products are increasing. Efforts to increase public health safety standards aimed at legitimately reducing the risks of human and animal disease have focused internationally on standards to regulate the movement of livestock products. There is concern, though, that measures to regulate these standards internationally, such as (...) the WTO SPS measures that in part aim to open international markets, may marginalize small-scale poor producers. The cycle of poverty they are trying to escape through livestock production may, in fact, widen, leading to increased global poverty, malnutrition, and disease. Developing and developed nations alike should be concerned with public and private efforts to address appropriate food safety policies to reduce the likelihood of this effect. Analysis of the impact on small-scale livestock farmers is needed, as well as solutions that consider joint public and private sector initiatives. Costly farm to table tracking systems are not an option, but locally orchestrated vertically integrated systems may have merit in reducing food safety risks and in providing small-scale farmers with increased access to markets, locally and internationally. Increased scientific and technical capacity, and training of WTO officials from developing nations is also needed. (shrink)

Berichte zur Wissenschaftsgeschichte, Volume 45, Issue 1-2, Page 245-260, June 2022.

Some of the authors of the essays on Chinese philosophers prefer the pin yin system of romanization for Chinese names and words, while others prefer the Wade‐Giles system. Given that both systems are in wide use today, important names and words are given in both their pin yin and Wade‐Giles formulations. The author's preference is printed first, followed by the alternative romanization within brackets.

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

How can the development of ideas in a scientific field be studied over time? We apply unsupervised topic modeling to the ACL Anthology to analyze historical trends in the field of Computational Linguistics from 1978 to 2006. We induce topic clusters using Latent Dirichlet Allocation, and examine the strength of each topic over time. Our methods find trends in the field including the rise of probabilistic methods starting in 1988, a steady increase in applications, and a sharp decline of research (...) in semantics and understanding between 1978 and 2001, possibly rising again after 2001. We also introduce a model of the diversity of ideas, topic entropy, using it to show that COLING is a more diverse conference than ACL, but that both conferences as well as EMNLP are becoming broader over time. Finally, we apply Jensen-Shannon divergence of topic distributions to show that all three conferences are converging in the topics they cover. (shrink)

Elite athletes, coaches and high-performance staff are exposed to a range of stressors that have been shown to increase their susceptibility to experiencing mental ill-health. Despite this, athletes may be less inclined than the general population to seek support for their mental health due to stigma, perceptions of limited psychological safety within sport to disclose mental health difficulties and/or fears of help-seeking signifying weakness in the context of high performance sport. Guidance on the best ways to promote mental health within (...) sporting environments is increasing, though current frameworks and position statements require greater focus on a whole of system approach, in which the needs of athlete, coaches and high-performance staff are considered within the context of the broader ecological system in which they operate and perform. This paper synthesizes existing research, reviewed for translatability by mental health professionals working in elite sport, to provide an evidence-informed framework with real world utility to promote mentally healthy environments for all stakeholders in elite sporting organizations, from athletes through to administrators. Recommendations are provided to positively impact the mental wellbeing of athletes and support staff, which may in turn influence athletic performance. This framework is intended to provide sporting organizations with evidence-informed or best practice principles on which they can develop or progress their policies to support mental health promotion and prevent the onset of mental health difficulties. It is intended that the framework can be adapted or tailored by elite sporting organizations based upon their unique cultural, contextual and resourcing circumstances. (shrink)

A significant portion of the world’s text is tagged by readers on social bookmarking websites. Credit attribution is an inherent problem in these corpora because most pages have multiple tags, but the tags do not always apply with equal specificity across the whole document. Solving the credit attribution problem requires associating each word in a document with the most appropriate tags and vice versa. This paper introduces Labeled LDA, a topic model that constrains Latent Dirichlet Allocation by defining a one-to-one (...) correspondence between LDA’s latent topics and user tags. This allows Labeled LDA to directly learn word-tag correspondences. We demonstrate Labeled LDA’s improved expressiveness over traditional LDA with visualizations of a corpus of tagged web pages from del.icio.us. Labeled LDA outperforms SVMs by more than 3 to 1 when extracting tag-specific document snippets. As a multi-label text classifier, our model is competitive with a discriminative baseline on a variety of datasets. (shrink)

review of Philosophy of Economics by C. Dyke.

In lieu of an abstract, here is a brief excerpt of the content:172. THE HUME LITERATURE FOR 1981 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; jê9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1980 were listed in Hume Studies for the last four Novembers. What follows here will bring the record up to (...) the end of 1981. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPReview Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly fol· low the British Standard (no. 4148). BAGOLINI, L. 'Legal Obligation in Hume', Hume Studies 7, 85-93. BAIER, A. 'Frankena and Hume on Points of View', The Monist 64, 342-58. BATTERSBY, C. 'An Enquiry concerning the Humean Woman', Philosophy 56, 303-12. 173. BEAUCHAMP, T. L. & ROSENBERG, A. Hume and the Problem of Causation, (xxv, 340 pp.) New York. [PB 23 (1982) 129-48 (Mackie, Flew, Beauchamp & Rosenberg) ] BOTWINICK, A. 'Hume on Is-Ought', Auslegung 8, 19-30. BURNS, R. M. The Great Debate on Miracles, esp. chs. 6-8. Lewisburg, London & Toronto. COSTA, M. J. 'Hume and Justified Belief, Can. J. Phil. 11, 219-28. CRONIN, R. Shelley's Poetic Thoughts, 77-83. London. DE MARTELAERE, P. 'Hume's "Gematigd" Scepticisme: Futiel of Fataal', Tijdschrift voor Filosofie 43, 427-64. DILMAN, I. Studies in Language and Reason, chs. 4-5. London. FARR, W. Hume and Kant: Studienbuch zum Erkenntsnisproblem. (250 pp.) Freiburg & Munich. FEINSTEIN, R. 'Some Problems in Humean Philosophy', Ind. phil. Q. 8, 527-32. FLAGE, D. E. 'Hume's Relative Ideas', Hume Studies 7, 55-73. GARCIA ROCA, J. Positivismo e Ilustración : La filosofía de David Hume. (304 pp.) Valencia. GARRETT, D. 'Hume's Self-Doubts about Personal Identity', PR 90, 337-58. GUPTA, B. 'Scepticism: Ancient "East" and Modern "West"', Ind. phil. Q. 9, 29-44. HAAKONSSEN, K. The Science of a Legislator, the Natural Jurisprudence? of David Hume and Adam Smith. Cambridge. HALL, R. 'The Hume Literature for 1980', Hume Studies 7, 184-90. íiARRISON, J. Hume's Theory of Justice. (xxvi, 304 pp.) Oxford. [THES no. 440 (3 Apr. 1981) 15] IMLAY, R. A. 'Hume's Of Scepticism with regard to reason: A Study in Contrasting Themes', Hume Studies 7, 121-36. JOHNSON, 0. A. 'Hume's "True" Scepticism', Pacific phil. Q. 62, 403-10. JONES, G. E. 'Vindication, Hume, and Induction', Can. J. Phil. 12, 119-29. 174. KING, J. 'Hume's Classical Theory of Justice', Hume Studies 7, 32-54. KULENKAMPFF, J. 'David Hume (1711-1776)', in 0. Hoffe, Klassiker der Philosophie, vol. 1, 434-56. Munich. LOEB, L. E. From Descartes to Hume, sec. 39 (354-63). Ithaca & London. MACLEOD, A. "Rule-Utilitarianism and Hume's Theory of Justice', Hume Studies 7, 74-84. MAHER, P. 'Probability in Hume's Science of Man', Hume Studies 7, 137-53. MALHERBE, M. 'Les études humiennes: anatomie et problèmes1, Archives de Philosophie 44, 637-71. MILLER, D. Philosophy and Ideology in Hume's Political ThoughtT (218 pp.) Oxford. [London Rev, of Bks 4 (1982), no. 7, 22-4; PB 23 (1982) 206-9] MONTEIRO, J. P. 'Hume's Conception of Science', JHP 19, 327-42. NEWMAN, R. 'Hume on Space and Geometry', Hume Studies 7, 1-31. NIELSON, H. A. 'Inference and Experience in Hume's Enquiry', Phil. Res. Archives 7, no. 1471. NORTH, T. 'What if I'm Indifferent?', Phil. Investigations 4, 24-37. PAPPAS, G. S. 'On McRae's Hume', Hume Studies... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:94. THE HUME LITERATURE FOR 1976 A fairly complete coverage of the recent Hume literature up to 1970 is available in my booklet, A Hume Bibliography from 1930 (York, 1971; obtainable direct from the author, post free, on payment of jé 1.25 within the U.K., c^3.00 or $8.00 elsewhere). Coverage up to 1975 is obtained when this is combined with the addenda and supplement published in the Philosophical Quarterly (...) in January 1976. What follows here will bring the record up to the end of 1976. Readers are invited to inform me of any omissions. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year. In a forthcoming book (Edinburgh University Press; probable title, Fifty Years of Hume Scholarship) I have tried to provide all that the student of Hume needs as a guide to the secondary literature: an introductory essay on the development of Hume scholarship up to the present time, thorough coverage of the Hume literature from 1925 to 19 76, with indexing by author, language, and subject, and also a list of the main writings on Hume earlier this century. The following abbreviations of journal titles have been used: APQ American Philosophical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PBA Proceedings of the British Academy PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie 95. RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious. ALEJANDRO, de, J. M. 'El atomismo gnoseologico de David Hume (1711-1776)', Pensamiento 32, 383-403. ANDERSON, R. F. 'The Location, Extension, Shape, and Size of Hume's Perceptions', in Livingston & King (see below), 153-71. ARDAL, P. S. 'Some Implications of the Virtue of Reasonableness in Hume's Treatise', in Livingston & King, 91-106. ARDLEY, G. 'Hume's Common Sense Critics', RIP 30, 104-2 5. ATKINSON, R. F. 'Hume on the Standard of Morals', in Merrill & Shahan (see below), 25-44. BAGOLINI, L. David Hume e Adam Smith: Elementi per una ricerca di filosofia giuridica e politica. Bologna. BAYLES, M. D. 'Hume on Blame and Excuse', Hume Studies 2, 17-35. BEANBLOSSOM, R. E. 1A New Foundation for Humean Scepticism1, Phil. Studies 29, 207-10. BEAUCHAMP, T. L. 'An Analysis of Hume's Essay "On Suicide"', RM 30, 73-95. BERfIAN, D. "David Hume on the 1641 Rebellion in Ireland', Studies: a Quarterly Review 65, 101-102. BIRO, J. I. 'Hume on Self-Identity and Memory", RM 30, 19-38. BJELKE, J. F. 'Wirklichkeitserkenntnis und Wirklichkeitsimagination bei Hume', Archiv für Geschichte der Phil. 58, 23-39. BOATRIGHT, J. R. 'Hume's Account of Moral Sentiment", RIP 30, 79-90. BOSSERT, P. J. "Hume and Husserl on Time and Time-Consciousness ", J. Br. Soc. Phenomenol. 7, 44-52. 96. BURNS, S. "The Humean Female", Dialogue 15, 415-2 4. [425-40.] BUTLER, R. J. ' Distinctiones Rationis, or the Cheshire Cat which left its smile behind it", PAS 76, 165-76. BUTLER, R. J. 'Hume's Impressions', in Royal Inst, of Phil. Lectures, Vol. 9, 122-36. CAPALDI, N. 'Hume's Theory of the Passions', in Livingston & King, 172-90. CHERRY, C. 'Nature, artifice and moral approbation", PAS 76, 265-82. COHEN, R. 'The Rationale of Hume's Literary Inquiries', in Merrill & Shahan, 97-115. COLVER, A. W. David Hume, The Natural History of Religion and PRICE, J. V. David Hume, Dialogues concerning Natural Religion. Oxford. [PB_ 18 (1977), 49-54. ] COURTENAY, W. J. et al. Ockham, Descartes, and Hume: Self-Knowledge, Substance, and Causality. Madison, Wis. CONNON, R. W. 'Some Hume MS Alterations on a Copy of the Abstract', JHP 14, 353-6. DAVIDSON, D. 'Hume's cognitive theory of pride', JP- 73, 744-57. DAVIE, W. 'Hume's Catalog of Virtue and Vice', in Merrill & Shahan, 45-57. DERATHÉ, R. 'L'obligation politique selon Hume', RIP 30, 91-103. ESPOSITO, J. L. 'Hume and the Transcendental Idealists', Southern J. Phil. 14, 431-42. FALK, W. D. 'Hume on Is and Ought', Canadian J... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:86. THE HUME LITERATURE FOR 1977 In my recently-published book, Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; ^ 5.50), the reader will find a thorough coverage of the Hume literature from 1925 to 1976, with lists of the main earlier writings on Hume, all indexed by author, language, and subject. What follows here will bring the record up to the end of 1977.· Readers (...) are invited to inform me of any omissions. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PBA Proceedings of the British Academy PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard. ÄRDAL, P. S. 'Convention and Value',in G. P. Morice, David Hume, Bicentenary Papers,51-68. Edinburgh. ÁRDAL, P. S. 'Another Look at Hume'sAccount of Moral Evaluation', JHP 15, 405-21. 87. BERK, E.? Note on Hume's Treatise I. iv. 1', Mind 86, 118-19. BERLIN, I. 'Hume and the Sources of German Anti-Rationalism', in Morice, op. cit., 95-116. BERRY, C. J. 'From Hume to Hegel: The Case of the Social Contract', JHI 38, 691-703. BOTWINICK, A.? Case for Hume's Nonutilitarianism', JHP 15, 423-35. BRADLEY, M. C. 'Stove on Hume', Australas. J. Phil. 55, 69-73. BRANDT, R. 'The Beginnings of Hume's Philosophy', in Morice, op. cit., 117-27. BRICKE, J. 'Hume on Self-Identity, Memory and Causality', in Morice, op. cit., 167-74. BRITTON, K. 'Hume on some Non-Natural Distinctions', in Morice, op. cit., 205-9. BURKS, A. W. Chance, Cause, Reason, esp. 128-42 ('Hume's thesis on the justification of induction'). Chicago. CASSIDY, J. 'The Nature of Hume's Inductive Scepticism: A Critical Notice', Ratio 19, 47-54. (on Stove 1973) COHEN, E. D. 'Hume's Fork', Sth. J. Phil. 15, 443-55. CONNON, R. W. 'The Textual and Philosophical Significance of Hume's MS Alterations to Treatise III ', in Morice, op. cit., 186-204. [PQ 28 (1978), 265-8] CONNON, R. W. & POLLARD, M. On the Authorship of "Hume's" Abstract', PQ 27, 60-6. CORSANO, A. 'Vico et Hume face au problème religieux', Archives de Phil. 40, 241-50. DAVIE, G. E. 'Edmund Husserl and "the as yet, in its most important respect, unrecognised greatness of Hume",' in Morice, op. cit., 69-76. DAVIS, J. W. 'Hume on Qualitative Content', in Morice, op. cit., 175-80. DELEULE, D. Hume, Lettre d'un Gentilhomme à son ami d'Edimbourg, présentation, traduction et notes. Paris. (French translation, with facing original, of A Letter from a Gentleman, Edinburgh, 1745) 88. DÉME", N. 'La Méthode Newtonienne et les Lois Empiriques de l'Anthropologie dans Traité II', in Morice, op. cit., 139-45. FORBES, D. 'Hume's Science of Polities', in Morice, op. cit., 39-50. FORCE, J. E. 'Hume in the Dialogues, the Dictates of Convention, and the Millennial Future State of Biblical Prophecy', S. -west. J. Phil. 8, 131-41. GAWLICK, G. 'Hume and the Deists: a Reconsideration', in Morice, op. cit., 128-38. GLOSSOP, R. J. 'In defence of David Hume', Australas. J. Phil. 55, 59-63. GLOUEERMAN, M. 'Hume on Modes', Hume Studies 3, 32-50. GUPTA, B. 'Buddha and Hume: A Popular Comparison Revisited ', Int. Phil. Q. 17 (1977), 135-46. HALL, R. 'The Hume Literature for 1976', Hume Studies 3, 94-102. HEALY,. M. 'Substance and Spiritual Substance - A criticism of David Hume', Alethe ia (Irving, Texas) 1 (1977), 159-83. HEDENIUS, I. Filosofien i ett föränderligt samhälle, 37-59 ( ' Värdeteorierna hos Hume': the value-theories in Hume). Stockholm. HINCKFUSS, I. 'Stove, Induction and the Irish', Australas. J. Phil. 55, 64-8. HISKES... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:429 THE HUME LITERATURE FOR 1985 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. (The book is still in print.) Publications of the years 1977 to 1984 were listed in previous issues of Hume Studies. What follows here will bring the (...) record up to the end of 1985. Readers are invited to inform me of any omissions, and keenly requested to send me offprints of their own articles and reviews. Hardly any do so at present, and it would greatly ease the labour of collection. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of this annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly HPQ History of Philosophy Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement 430 Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). AGASSI, J. "The Unity of Hume's Thought", Hume Studies (10th Anniv. Issue), 87-109. AUSTIN, W. H. "Philo's Reversal", Phil. Topics 13, no. 2, 103-12. BADIA CABRERA, M. A. "Hume's Natural History of Religion: Positive Science or Metaphysical Vision of Religion", Diálogos 20, 71-8. BAIER, A. Postures of the Mind, ch. 10 ("Promises, Promises, Promises"), ch. 11 ("Civilizing Practices"). London, etc. BEHAN, D. P. "Hume's Labyrinth", HPg 2, 309-22. BENNETT, D. "Hume's Pride", in B. Vermazen, Essays on Davidson, 89-91. Oxford. BIRO, J. L. "Hume and Cognitive Science", HPQ 2, 257-74. BLANDINO, G. "Le causalitate. Discussion sur le criticas de D. Hume" [in Interlingua, with French and English], Aquinas 28, 247-57. BRICKE, J. "Locke, Hume and the Nature of Volitions", Hume Studies (10th Anniv. Issue), 15-51. BROOKS, D. "Hume's Bundle Theory of the Mind", S. African J. Phil. 4, 75-84. BROOKS, D. H. M. "Strawson, Hume, and the Unity of Consciousness", Mind 94, 583-6. CAMPBELL, K. "John Passmore and Hume's Moral Philosophy", Hume Studies 11, 109-24. CAPALDI, N. "The Historical and Philosophical Significance of Hume's Theory of the Self", in A.J. Holland, Philosophy, Its History and Historiography, 271-85, Dordrecht, etc. 431 CARLSON, G. R. "Hume and the Moral Realists", Australas. J. Phil. 63, 407-18. CHAKRABARTI, T. K. "Hume's Definitions of Cause", J. Indian Council Phil. Res., 67-75. CHEN, W. -S. Article (in Chinese) on Hume on personal identity, in Phil. Rev. (Taiwan) 8, 123-42. CLARK, S. R. L. "Hume, Animals and the Objectivity of Morals", P£ 35, 117-33. CLERO, J. P. La philosophie des passions chez David Hume. (301 pp.) Paris. DANIEL, S. C "The Problem of Identity of Objects in Hume's Philosophy", Indian Phil. Q. 12, 1916. DAVIE, W. "Hume on Morality, Action, and Character", HPQ 2, 337-48. DEWITT, R. "Hume's Probability Argument of I, iv, 1", Hume Studies 11, 125-40. DONNICI, R. "Husserl sull' etica di Hume. Dalle lezioni inedite del 1902", Rivista di storia della filosofia 40, 449-70. ENC, B. "Hume on Causal Necessity: A Study from the Perspective of Hume's Theory of Passions", HPQ 2, 235-56. FERREIRA, M.J. "Hume's Naturalism - 'Proof and Practice", P£ 35, 45-57. FLAGE, D.E. "Hume on Memory and Causation", Hume Studies (10th Anniv. Issue), 168-88. [11 (1985) 166-72] FLAGE, D.E. "Perchance to Dream: A Reply to Traiger", Hume Studies 11, 173-82. (on Traiger 1985b) FLAGE, D.E. "Hume's Ethics", Phil. Topics 13, no. 3, 71-88. FLEW, A. "Impressions and Experiences: Public or Private?", Hume Studies 11, 183-91. 432 FOGELIN, R.J. Hume's Skepticism... (shrink)

According to the somatic mutation theory (SMT), cancer begins with a genetic change in a single cell that passes it on to its progeny, thereby generating a clone of malignant cells. It is strongly supported by observations of leukemias that bear specific chromosome translocations, such as Burkitt's lymphoma, in which a translocation activates the c‐myc gene, and chronic myeloid leukemia (CML), in which the Philadelphia chromosome causes production of the BCR‐ABL oncoprotein. Although the SMT has been modified and extended to (...) encompass tumor suppressor genes, epigenetic inheritance, and tumor progression through accumulation of further mutations, perhaps the strongest validation comes from the successful treatment of certain malignancies with drugs that directly target the product of the mutant gene.magnified imageDavid Vaux is at the Walter and Eliza Hall Institute and La Trobe Institute for Molecular Science, Melbourne, Australia. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:131. THE HUME LITERATURE FOR 1978 The Hume Literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; J¿ 5.50), which also lists the main earlier writings on Hume. Publications of the year 1977 were listed in Hume Studies last November. What follows here will bring the record up to the end of 1978. (...) Readers are invited to inform me of any omissions, and to send me offprints of their own articles. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQAmerican Philosophical Quarterly JHIJournal of the History of Ideas JHPJournal of the History of Philosophy JPJournal of Philosophy PASProceedings of the Aristotelian Society PBPhilosophical Books PQPhilosophical Quarterly PRPhilosophical Review RIPRevue Internationale de Philosophie RMReview of Metaphysics TLSTimes Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). ANSCOMBE, G. E. M. 'Rules, Rights, and Promises', Midwest Studies in Phil. 3, 318-23. ARMSTRONG, D. M. Universals and Scientific Realism, vol. 2: A Theory of Universals, 85-90. Cambridge. ATTFIELD, R. God and the Secular, esp. chs. 5-6. Cardiff. 132. BAIER, A. 'Hume's Analysis of Pride', JP 75, 27-40. (on Davidson 1976) BALDI, M. 'Le edizioni italiane dei Saggi economici di David Hume', Riv. crit. Stor. FiI. 33, 275-96. BARNOUW, D. 'Skepticism as a Literary Mode - Hume, David and Musil, Robert', Mod. Lang. Notes 93, 852-70. BASU, D. K. 'Who is the Real Hume in the Dialogues?', Indian Phil. Q. 6, 21-8. BEAUCHAMP. see ROBINSON. BECK, L. W. Essays on Kant and Hume. New Haven & London, (includes reprints of his 1967a and b, and 1974, and the first Eng. tr. of his 1969; also a new paper,? Prussian Hume and a Scottish Kant', on pp. Ill ff) BLACKMAN, L. L. 'The Logical Impossibility of Miracles in Hume', Int. J. Phil. Relig. 9, 179-87. BOSS, G. "1I Promise": Les fonctions du langage chez Hume et Austin', Revue Théol. et Phil. 110, 29-48. BRACKEN, H. M. 'Bayle, Berkeley, and Hume', EighteenthCentury Studies 11, 227-45. BROWNSEY, P. F. 'Hume and the Social Contract', PQ 28, 132-48. BURKE, J. J. 'Hume's History of England: Waking the English from a Dogmatic Slumber', Studies in 18th-century Culture 7, 235-50. CAPALDI, N. 'Hume as Social Scientist', RM 32, 99-123. CARNIE, R. H. 'The Hume-Hailes Relationship', Forum for Mod. Lang. Studies 14, 289-303. CARTWRIGHT, N. 'Comments on Wesley Salmon's "Science and Religion..."', Phil. Studies 33, 177-83. COHEN, Benjamin. 'Contrariety and Causality in Hume', Hume Studies 4, 29-39. CONNIFF, J. 'Hume on Political Parties: The Case for Hume as a Whig', Eighteenth-Century Studies 12, 150-73. CUMMINS, R. 'The Missing Shade of Blue', PR 87, 548-65. DOUBLE, R. 'Hume's Empirical Argument for Empiricism', Sth J. Phil. 16, 329-38. 133. ERDE, E. L. 'Founding Morality: "Hume v. Plato" or "Hume & Plato"?', S. -west. J. Phil. 9, 19-25. FARR, J. 'Hume, Hermeneutics, and History: A "Sympathetic" Account', Hist. & Theory 17, 285-310. FLEW, A. 'Inconsistency within a Reconciling Project', Hume Studies 4, 1-6. GASKIN, J. C. A. Hume's Philosophy of Religion, (xi, 188 pp.* London. [Times Higher Ed. Suppl. 21 July (1978), 17; TLS 28 July (1978), 863; RB 20 (1979), 68-71] GINSBERG, R. 'Hume and the Social Contract', EighteenthCentury Life 4, 91-4. GUPTA, G. 'Another Look at the Buddha-Hume "Connection"', Indian Phil. Q. 5, 371-86. GUPTA, R. 'Certain Aspects of the Causal Theories of the Buddhist, Hume and Mill', Indian Phil. Q. 5, 319-35. HAAKONSSEN, K. 'Hume's Obligations', Hume Studies 4, 7-17. HACKING, I. 'Hume's Species of Probability', Phil. Studies 33, 21-37. HALL, R. Fifty Years of Hume Scholarship: A bibliographical guide. (x, 150 pp.) Edinburgh. [British Book News... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:162. THE HUME LITERATURE FOR 1979 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship : A Bibliographical Guide (Edinburgh University Press, 1978; ¿J 5. 50), which also lists the main earlier writings on Hume. Publications of the years 1977 and 1978 were listed in Hume Studies for the last two Novembers. What follows here will bring the record (...) up to the end of 1979. Readers are invited to inform me of any omissions, and to send me offprints of their own articles. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography covering the previous year, with addenda consisting of items omitted through ignorance in previous years. References to recentlyappearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQ American Philosophical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Aristotelian Society PB Philosophical Books PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British Standard (no. 4148). AIKEN, H. D. 'An Interpretation of Hume's Theory of the Place of Reason in Ethics and Polities', Ethics 90, 66-80. 163. ARDAO, A. 'Hume en Latinoamerica', Revista Venezolana de Fil., 143-6. BAIER, A. 'Hume on Heaps and Bundles', APQ 16, 285-96. BAIER, A. 'Good Men's Women: Hume on Chastity and Trust', Hume Studies 5, 1-19. BATTERSBY, C. 'Hume, Newton and "the Hill called Difficulty "', in S. C Brown, Philosophers of the Enlightenment (Royal Inst. Phil. Lectures, 12), 31-55. BATTERSBY, C. 'The Dialogues as Original Imitation: Cicero and the Nature of Hume's Skepticism', in D. F. Norton et al., McGiIl Hume Studies, 239-52. BEAUCHAMP, T. L. 'Self Inconsistency or Mere Self Perplexity ', Hume Studies 5, 37-44. BECK, L. W.? Prussian Hume and a Scottish Kant' in D. F. Norton et al.,· op. cit., 63-78. (repr. of 1978 paper. ) BELL, A. 'Some Spurious Hume Documents', Notes & Queries 26, 561. BIRO, J. I. 'Hume's Difficulties with the Self, Hume Studies 5, 45-54. BRANDT, R. 'David Hume: Neuere Bücher, Vorträge, Aufsätze', Philosophische Rundschau 26, 187-97. BROWN, S. C. 'The "Principle" of Natural Order: o£ What the Enlightened Sceptics did not doubt', in S. C. Brown [see BATTERSBY], 56-76. BUTT, J. The Mid-Eighteenth Century, 222-8, 312-14, 354-7. (The Oxf. Hist, of Eng. Lit., 8.) Oxford. CAPALDI, N. 'The Problem of Hume and Hume's Problem', introduction to D. F. Norton et al., op. cit., 3-21. CASULLO, A. 'Reid and Mill on Hume's maxim of conceivability ', Analysis 39, 212-19. CLARK, L. M. G. & LANGE, L. The Sexism of Social and Political Theory. Toronto"^ (includes reprints of Burns 1976 and Lacoste 1976) CONNON, R. W. 'The Naturalism of Hume Revisited', in D. F. Norton et al., op. cit. 121-45. COTTLE, C E. 'Justice as Artificial Virtue in Hume's Treatise', JHI 40, 457-66. 164. CRAIG, E. J. David Hume: Eine Einführung. in seine Philosophie. (144 pp.) Frankfurt am Main. DAVIE, G. E. 'Berkeley, Hume, and the Central Problem of Scottish Philosophy', in D. F. Norton et al., op. cit., 43-62. DEL BARCO COLLAZOS, J. L. 'Sobre la teoría de la imaginaci ón en la filosofía de Hume', Anuario filosofico 12, 131-43. DELEULE, D. Hume et la naissance du libéralisme économique. (400 pp.) Paris. FLEW, A. 'The Red Queen at Substraction? ', Hume Studies 5, 110-11. FORBES, D. 'Hume and the Scottish Enlightenment', in S. C Brown [see BATTERSBY], 94-109. GASKIN, J. C. A. 'Hume, Atheism, and the "Interested Obligation" of Morality', in D. F. Norton et al., op. cit., 147-59. GAUTHIER, D. 'David Hume, Contractarian', PR 88, 3-38. GAWLICK, G. 'Zwischen Empirizismus und Skeptizismus: Neue Literatur zu David Hume- (I) ', Philosophische Rundschau 26, 161-86. GOOSENS, W. K. 'Stove and Inductive Scepticism', Australas... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:192. THE HUME LITERATURE FOR 1983 The Hume literature from 1925 to 1976 has been thoroughly covered in my book Fifty Years of Hume Scholarship: A Bibliographical Guide (Edinburgh University Press, 1978; £9.50), which also lists the main earlier writings on Hume. Publications of the years 1977 to 1982 were listed in Hume Studies in previous Novembers. What follows here will bring the record up to the end of (...) 1983. Readers are invited to inform me of any omissions, and to send me offprints of their own articles and reviews. The intention is to maintain a complete bibliographical record of critical work on Hume, by the regular publication in Hume Studies of an annual bibliography, with addenda consisting of items omitted through ignorance in previous years. References to recently-appearing reviews (of books from earlier lists) are given at the end. The following abbreviations of journal titles are used here: APQ American Philosohical Quarterly JHI Journal of the History of Ideas JHP Journal of the History of Philosophy JP Journal of Philosophy PAS Proceedings of the Arisotelian Society PB Philosophical Books PQ Philosophical Quarterly PR Philosophical Review RIP Revue Internationale de Philosophie RM Review of Metaphysics TLS Times Literary Supplement Other abbreviations should be obvious enough, and mainly follow the British standard (no. 4148). 193, ARNOLD, N. S. 'Hume's Skepticism about Inductive Inference', JHP 21, 31-55. BARKER, S. 'Hume on the Logic of Design', Hume Studies 9, 1-18. [19-24] BERMAN, D. 'David Hume and the Suppression of Atheism', JHP 21, 375-87. BOX, M.? Gloss on Goldsmith's Remark on Hume', Notes & Queries 30, 59-60. BRETT, N. 'Hume's Debt to Kant', Hume Studies 9, 5973. BROUGHTON, J. 'Hume's Skepticism about Causal Inference', Pacific phil. Q. 64, 3-18. CALVERT, B. 'Another Problem about Part IX of Hume's Dialogues', Int. J. Phil. Relig. 14, 65-70. COLWELL, G.G. 'Miracles and History', Sophia 22, 9-14. DARWALL, S. L. Impartial Reason, ch. 5 ('Hume's Internalism1 ). Ithaca, N. Y. DEL VECCHIO, M. 'Un Impotesi di Lettura Esegetlica del "Dubbio Scettico" Humeano', Riv. crit. Stor. FiI. 38, 457-64. FOGELIN, R. J. 'The Tendency of Hume's Skepticism', in M. Burnyeat, The Skeptical Tradition, 397-412. Berkeley, CaI. GASKIN, J. CA. 'Hume's Attenuated Deism', Arch. Gesch. Phil. 65, 160-73. GEMES, K.? Refutation of Inductive Scepticism', Australas. J. Phil. 61, 434-8. GUTTENPLAN, S. 'Hume and Contemporary Ethical Naturalism', Midwest Stud. Phil. 8, 309-20. HARRIS, H. S. 'Hume and Barker on the Logic of Design', Hume Studies 9, 19-24. HARTSHORNE, C 'Hume's Metaphysics and its Influence', in C Hartshorne, Insights and Oversights of Great Thinkers, 136-50. HIRSCH, E. 'Hume's Distinction between Genuine and Fictitious Identity', Midwest Stud. Phil. 8, 321-38. 194, IMMERWAHR, J. 'David Hume, Sexism, and Sociobiology ', Sth. J. Phil. 21, 359-70. KIVY, P. 'Hume's Neighbour's Wife: An Essay on the Evolution of Hume's Aesthetics', Br. J. Aesth. 23, 195-208. KUEHN, M. 'Kant's Conception of "Hume's Problem"', JHP 21, 175-93. KUEHN, M. 'Hume's Antinomies', Hume Studies 9, 25-45. McCRACKEN, CJ. Malebranche and British Philosophy, ch. 7. Oxford. McLYNN, F.J. 'Jacobitism and David Hume: The Ideological Backlash Foiled', Hume Studies 9, 171-99. MALHERBE, M. 'La notion de circonstance dans la philosophie de Hume', Hume Studies 9, 130-49. NATHAN, G. J.? Humean Pattern of Justification', Hume Studies 9, 150-70. NIELSEN, K. 'Hobbesist and Humean Alternatives to a Religious Morality', Int. J. Phil. Relig. 14, 33-47. PENELHUM, T. 'Natural Belief and Religious Belief in Hume's Philosophy', P£ 33, 166-81. [182-6] PONKO, T. A. 'Artificial Virtue, Self-interest, and Acquired Social Concern', Hume Studies 9, 4658. ROD, W. 'The Rationalist Theory of Double Causality as an Object of Hume's Criticism', Erkenntnis 19, 315-29. ROHATYN, D. 'Hume's Dialectical Conceits: The Case of Dialogue XII', Phil. & phenomenol. Res. 43, 519-32. RUSSELL, P. 'On the Naturalism of Hume's "Reconciling Project"', Mind 92, 593-600. SCARRE, G. 'What was Hume's worry about Personal Identity?', Analysis 43, 217-21. SCARRE, G. 'Was Mill Really Concerned with Hume's Problem of... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Comme Elle Respire:Memory of Breath, Breath of MemoryFrédérique Berthet (bio)Translated by David F. Bell (bio)La poésie est un système de respiration, c'est fait pour mieux respirer.[Poetry is a respiration system, it's made for breathing better.]—Erri De Luca- Stop!- What?- I can hear you breathing!...- Stop!- Breathing?- Yes!—Paul Thomas AndersonLittle paper-fish cutouts have been placed on the ground, on the carpet.We're in the reassuring '70s stylishness of a doctor's (...) office. The carpet is soft and glistens like in interior decoration magazines, it's with it, in. We couldn't care less about what Dyson vacuum cleaners and "purifiers" boast they can eliminate several decades later: acarids, those microscopic domestic arthropods, human parasites (notably), and airborne vectors of infectious disease (colds, coughs, respiratory distress). No, in the spring of 1975, innocently and self-satisfyingly, the urbane doctor flaunts the opulent carpet with curly pile in his luxury apartment with its state-of-the-art waiting room.In this grand interior of a medical office, a man in a white coat plies his important trade. For example, that day a little girl is re-learning how to breathe. One might think that exhaling and inhaling is learned for life—je t'aime comme je respire, elle parle comme elle respire, il ment comme il respire1—from the very first cry at birth. But in fact, sometimes in life breathing gets stuck between the nasal cavity and the bronchial tubes, between the respiratory tract and the lungs. Progressively, imperceptibly, the organism is short of air, a malicious infection spreads and impairs [End Page 92] alveolar diffusion to the point of respiratory exhaustion: Is it serious, doctor? We must act quickly, very quickly. How to liquify what stopped up the system one day to the point of blocking it—the doctors know what to do.This doctor undertook long, arduous and learned studies. He knows functionally how a living being breathes, how a child lives organically. He can also re-teach the little girl what she no longer knows how to do: inhale, exhale using the full volume of the thoracic cage, regulating the ventilatory flow, solidifying the invisible membranes. In the child's family, everyone knows (and knows how to do) important things, but no one undertook extensive studies, much less studies of the aerial exchanges in the human body. This special knowledge possessed by the doctor (unless special means something else unspoken that would explain why this specific doctor was chosen rather than any other) surrounds him with a padding of respect that creates (and the little girl feels this) a sort of protective continuum between him and the walls within which he sees her, where he practices his kind of calm and slow urbane medicine. It's far from the formidable hospital she has just left, with its spherical apparatus next to the bed aspirating the red and yellow pleural liquid, the "treatment room" where the surgeon, the "butcher" as the nurses call him among themselves, manipulated the drain without anesthesia, with no regard for the child's suffering. The doctor, and his place in the elevated tower, even though they are not to be confused, make for a cozy reception space in which one is comfortable, even in passing.This doctor—who is, in truth, a massage-physiotherapist—is located in a designer high-rise building with a façade decorated by white, pointed features that manifest a will toward an architectural act. On the ground floor, the entrance hall is finished in dark-veined, clear brown marble, and the entry threshold between the exterior and interior is marked by large transparent glass panes that must be manipulated with care. The entrance hall has an intimidating sonority and a useless cold nudity from which one escapes in an elevator where one is surrounded by mirrors and gold buttons and in which one speeds upward silently toward floors, clouds.The designer high-rise is located at the outskirts, the outskirts of a city of recent Olympic stature, where several years earlier Olympic athletes were welcomed and trained to increase their respiratory capacity and... (shrink)

These volumes provide a large introduction to the works of modern value theory from their beginnings in J. Bentham, F. Nietzsche, and H. Lotze to the more recent Anglo-American studies. Volume I is concerned with "the German-Language Group." Extensive discussion is devoted to the views of F. Brentano, A. Meinong, C. von Ehrenfels, J. C. Kreibig, E. Heyde, H. Rickert, H. Münsterberg, M. Scheler, K. Wiederhold, W. Stern, F. Wilken, M. Beck, and V. Krafts. It provides a good conspectus of (...) varieties of nineteenth century value theories. The author aims at an exposition rather than critical treatment of the various philosophers. Each chapter contains a useful bibliography. Of more contemporary interest is Volume II which deals with the Anglo-American Group. One finds here a detailed presentation of the theories of W. M. Urban, J. Dewey, B. Bosanquet, D. Prall, C. G. Shaw, R. B. Perry, D. H. Parkel, W. Stern, A. C. Garnett, J. N. Findlay, E. Brightman, B. E. Jessup, C. I. Lewis, R. Lepley, S. C. Pepper, Everett Hall, R. Hartman, and W. D. Lamont. Shorter discussions deal with works of A. L. Hillard, E. M. Adams, and K. Aschenbrenner. Liberal quotations from original sources are interspersed throughout the exposition. The clarification of issues is not always successful. The author does provide a good focus, however, for important passages from the works discussed. Regrettably, one finds an omission of the view of David Pole, the absence of a summary section on each theory discussed, and the absence of an index. Nevertheless, the students of value theory can find in this work a useful tool of research. The comprehensive scope provides a rich variety of contributions to the important field of value theory.—A.S.C. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Hume Studies Volume 29, Number 2, November 2003, pp. 267-282 Skepticism and Philo's Atheistic Preference DAVID O'CONNOR [H]owever consistent the world may be... with the idea of... a very powerful, wise, and benevolent Deity... it can never afford us an inference concerning his existence. The consistence is not absolutely denied, only the inference.1 The whole presents nothing but the idea of a blind nature, impregnated by a great (...) vivifying principle, and pouring forth from her lap, without discernment or parental care, her maimed and abortive children. (DNR, 211) The true conclusion is, that the original source of all things is entirely indifferent to all these principles, and has no more regard to good above ill than to heat above cold, or to drought above moisture, or to light above heavy. (DNR, 212) There may four hypotheses be framed concerning the first causes of the universe: that they are endowed with perfect goodness, that they have perfect malice, that they are opposite and have both goodness and malice, that they have neither goodness nor malice.... The fourth... seems by far the most probable. (DNR, 212) David O'Connor is Professor of Philosophy, Seton Hall University, South Orange, New Jersey 07079. e-mail: [email protected] 268 David O'Connor What I have said concerning natural evil will apply to moral, with little or no variation; and we have no more reason to infer, that the rectitude of the supreme Being resembles human rectitude than that his benevolence resembles the human. Nay, it will be thought, that we have still greater cause to exclude from him moral sentiments, such as we feel them; since moral evil, in the opinion of many, is much more predominant above moral good than natural evil above natural good. (DNR, 212) Thus Philo in part 11 of Hume's Dialogues concerning Natural Religion. I In the first of these passages, Philo is denying that the existence of "a very powerful, wise, and benevolent Deity" can justifiably be inferred from the facts of good and evil present to our experience. But power, wisdom, and benevolence are essential qualities of the God of traditional theism, thus Philo is here denying that the existence of such a being can justifiably be inferred from the empirical evidence of good and evil. The other passages show us Philo going further than this, indeed all the way to what seems to be a preference for moral atheism. The term is J. C. A. Gaskin's, and he defines it thus: "[moral atheism] will be [the position of] anyone who denies the existence of any god having moral attributes."2 In the second and third passages specifically, this prima facie preference is absolute ("[t]he whole presents nothing but the idea of a blind nature... without discernment" and "the original source of all things is entirely indifferent," respectively), while it is relative and more cautiously expressed in the fourth passage. And the fifth passage says at least as much as the first and perhaps as much as the second and third. Yet Philo very early in the book declares himself a skeptic on such metaphysical topics as "the origin of worlds" (DNR, 132), "the existence and properties of spirits" (DNR, 135), "the powers and operations of one universal spirit, existing without beginning and without end; omnipotent, omniscient, immutable, infinite" (DNR, 135). The principal reason he gives is the "weakness, blindness, and narrow limits of human reason... even in subjects of common life and practice" (DNR, 131). Considering these limits, surely it is very likely that "we have... got quite beyond the reach of our faculties" (DNR, 135) if and when we turn to such metaphysical topics as those he just listed. On these matters, which "run wide of common life... [t]he mind must remain in suspense... and it is that very suspense or balance, which is the triumph of skepticism" (DNR, 135-6). Hume Studies Philo's Atheistic Preference 269 While the first of the passages I quoted in the beginning clearly squares with this skeptical outlook, and so does at least part of the fifth, it would seem that the rest of the quoted material does not... (shrink)

CITATION: Ewuoso, C., Hall, S. & Dierickx, K. 2017. How do healthcare professionals manage ethical challenges regarding information in healthcare professional/patient clinical interactions? a review of concept- or argument-based articles and case analyses. South African Journal of Bioethics and Law, 10:75-82, doi:10.7196/SAJBL.2017.v10i2.610.

There are several branches of ethics. Clinical ethics, the one closest to medical decisionmaking, can be seen as a branch of medicine itself. In this view, clinical ethics is a unitary hermeneutics. Its rule is a guideline for unifying other theories of ethics in conjunction with the clinical context. Put another way, clinical ethics interprets the clinical situation in light of a balance of other values that, while guiding the decisionmaking process, also contributes to the very weighting of those values. (...) The case itself originates ideas, not only about which value ought to predominate in its resolution, but also provides the origin of clinical rules that can be used in other cases. These are interpretive rules. Some examples of these rules are presented as well. (shrink)

Like most other sciences, behavior analysis adopts an assumption of uniformity, namely that principles discovered under controlled conditions apply outside the laboratory as well. Since the boundary between public and private depends on the vantage point of the observer, observability is not an inherent property of behavior. From this perspective, private events are assumed to enter into the same orderly relations as public behavior, and the distinction between public and private events is merely a practical one. Private events play no (...) role in the experimental analysis of behavior, but they permit us to make sense of many commonplace phenomena where controlled observation is impossible but unsystematic data are available. Such interpretive exercises serve both to guide research and to displace occult explanations. (shrink)

What exactly is a genetic disease? For a phrase one hears on a daily basis, there has been surprisingly little analysis of the underlying concept. Medical doctors seem perfectly willing to admit that the etiology of disease is typically complex, with a great many factors interacting to bring about a given condition. On such a view, descriptions of diseases like cancer as genetic seem at best highly simplistic, and at worst philosophically indefensible. On the other hand, there is clearly some (...) practical value to be had by classifying diseases according to their predominant cause when this can be accomplished in a theoretically satisfactory manner. The question therefore becomes exactly how one should go about selecting a single causal factor among many to explain the presence of disease. When an attempt to defend such causal selection is made at all, the standard accounts offered (Koch's postulates, Hill's epidemiological criteria, manipulability) are all clearly inadequate. I propose, however, an epidemiological account of disease causation which walks the fine line between practical applicability and theoretical considerations of causal complexity and attempts to compromise between patientcentered and population-centered concepts of disease. The epidemiological account is the most basic framework consistent with our strongly held intuitions about the causal classification of disease, yet it avoids the difficulties encountered by its competitors. (shrink)

Reviews the connections between different kinds of nonmonotonic logic and the general idea of varying degrees of belief.

Applying general and statistical knowledge to individuals is difficult either on epidemiological or epistemological grounds. This paper examines these difficulties from the perspective of computer registers of epidemiological data.

Relevance logic is ordinarily seen as a subsystem of classical logic under the translation that replaces arrows by horseshoes. If, however, we consider the arrow as an additional connective alongside the horseshoe and other classical connectives, another perspective emerges. Relevance logic, specifically the system R, may be seen as the output of a conservative extension of classical consequence into the language with arrow.

In this paper I address three problems posed by modern medical technology regarding comatose dying patients. The first is that physicians sometimes hide behind the tests for whole-brain death rather than make the necessary human decision. The second is that the tests themselves betray a metaphysical judgment about death that may be ontologically faulty. The third is that discretion used by physicians and patients and/or family in deciding to cease treatment when the whole-brain death criteria may not be met are (...) sometimes open to challenge. In each of these problems I find that the operative concept of death relates to life itself. This point is expanded by examining the uses of the word death in our language and culture. From these I formulate an initial ontology of death. In it, death is described through a relationship with life, rather than as an absence of life, of consciousness, awareness, or sensation. This ontology then leads to a proposal for an ethics of discretion about the discontinuation of treatment for comatose patients. (shrink)